2020年4月28日 星期二

[研究發表] Stability of a Lupus Nephritis Case after One Year of Integrated Therapy 狼瘡性腎炎患者經過整合中西醫學治療一年後之穩定性

Stability of a Lupus Nephritis Case after One Year of Integrated Therapy
狼瘡性腎炎患者經過整合中西醫學治療一年後之穩定性
Wei-Ting Tseng1, Po-Hsuan Shih2,3, Hong-Chun Lin1, Pei-Wen Wu1, Yen-Ying Kung1,3,4 and  Ching-Mao Chang1,3,4*
1Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
2Department of Chinese Medicine, Cheng Hsin General Hospital, Taipei, Taiwan
3Institute of Traditional Medicine, National Yang-Ming University, Taipei, Taiwan
4Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan
*Corresponding Author: Dr. Ching-Mao Chang, M.D., Ph.D., Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Received: March 06, 2020; Published: April 17, 2020

Abstract

This case report revealed that how a stable condition of the patient with LN experienced accidentally with thrombocytopenia on early July 2019, which it is the most severe comorbidity of systemic lupus erythematosus and the patient’s platelets increased from 11 x 103 μL to 186 x 103 μL after receiving the integrated pulse-prednisolone therapy plus core CHM treatment, composed of “Jia- Wei-Xiao-Yao-San” (6g), “Yin-Chen-Hao-Tang” (6g), “Xie-Fu-Zhu-Yu-Tang” (6g), “A-Jiao” (0.25g), “Dan-Shan” (0.25g) and “Gou-Teng” (0.25g). Over the same 28 day period, her alanine transaminase (ALT) and aspartate transaminase (AST) also decreased from 103 U/L, and 116 U/L to 62 U/L and 89 U/L, respectively; and her dosage of prednisolone was reduced from 50 mg to 5 mg per day. This case report follow-up wants to clarify the stability of a LN case after continuous one year of integrated conventional medicine with core Chinese herbal medicine. And it also could provide some clues for treating the severe comorbidity in systemic lupus erythematosus patients, it will provide the whole and comprehensive views for this following-up case. However, the comorbidity of systemic lupus erythematosus should be clarified with a comprehensive view in the future.
Keywords: Systemic Lupus Erythematosus; Lupus Nephritis; Traditional Chinese Medicine; Integrated Medicine; Thrombocytopenia


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