[義診] 又到了一年一度的新竹尖石鄉義診

Introduction of Dr. Ching-Mao Chang (Update on 2023/04/30)

Ching-Mao Chang, M.D., Ph.D.  (張清貿, C.M. Chang)

Director, Division of Integrative Medicine Center for Traditional Medicine, Taipei Veterans General Hospital No.201, Sec. 2, Shipai Rd., Beitou District, Taipei City, Taiwan 11217, R.O.C TEL: +886-2-28757453 #304 E-Mail: tcmcmc@gmail.com Blog: http://tcmcmc.blogspot.tw/ ------------------------------------------------------ Dr.Ching-Mao Chang's personal introduction  Autoimmune Disease and Dry Eye Syndrome Objective Measurements Lab (AIDDES Lab) Director, Division of Integrative Medicine, Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan https://www.vghtpe.gov.tw/Docpersnr.action?tno=DOC4331B Assistant professor of Institute of Traditional Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan https://tmi.nycu.edu.tw/en/full-time-teachers-2/ching-mao-chang/ ------------------------------------------------------ ***張清貿醫師只有FB官方粉專跟這個LINE官方帳號，沒有其他的群組，請認明正確帳號。 _____________________________________________________________________________

Evidence-Based Traditional Chinese Medicine for Sjögren Syndrome

EBM in TCM for Sjögren Syndrome/Sicca syndrome

BIOGRAPHY

Dr. Chang is a Director/Attending Physician (M.D.) in the Division of Integrative Medicine, Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, and an Assistant Professor in the Faculty of Medicine, National Yang Ming Chiao Tung University (Taipei). Dr. Chang was awarded his Ph.D. from the Graduate Institute of Clinical Medical Sciences (GICM), Chang Gung University, Taoyuan, Taiwan. His Ph.D. study, The Efficacy of Chinese Herbal Formula on Sjögren's syndrome and its Mechanism of Anti-oxidative and Immune Modulatory Effects, reflects his ongoing fascination with the ability of TCM treatment to not only relieve but also modify the debilitating symptoms associated with Sjögren's syndrome, including gastrointestinal discomfort, poor appetite, xerostomia and aphthous ulcer. Since graduating with his Ph.D., Dr. Chang has received many tributes in recognition of his excellent guidance offered to younger clinicians and researchers, including "Best Teacher Award", "Traditional Chinese Medicine Excellent Academic Research Award", and "Distinguished Clinical Teaching Physician Award" from several institutions: Taipei Veterans General Hospital, the Taipei Chinese Medical Association, National Yang Ming Chiao Tung University, and the National Union of Chinese Medical Doctors’ Association.

RESEARCH INTERESTS

Dr. Chang specializes in traditional Chinese medicine and rheumatology. His main research interests involve TCM clinical trials, Sjögren’s syndrome, systemic lupus erythematosus, systemic sclerosis, and bioinformatics studies. As a key developer of the novel Chinese herbal medicine SS-1 (a triple combination of Chinese herbal preparations consisting of extracts of Gan-Lu-Yin, Sang-Ju-Yin, and Xuefu-Zhuyu-Decoction), he has applied SS-1 in the clinic with very successful outcomes in patients with Sjögren's syndrome. He is particularly keen on being involved in research collaborations that include biotechnology, bioinformatics and biopharmaceutics.

Education:

1. Ph.D., Graduate Institute of Clinical Medicine, Chang Gung University, Taoyuan, Taiwan
2. M.D., School of Chinese Medicine, China Medical University, Taichung, Taiwan

Current Employment:

1. Director, Division of Integrative Medicine, Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
2. Assistant professor, Institute of Traditional Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
3. Assistant Professor, Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan

Employment Record:

1. Visiting Research Scholar, Center for Complementary and Integrative Medicine, Division of Rheumatology, Tufts Medical Center, Boston, US
2. Attending physician (M.D.), Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
3. TCM Chief Resident Physician, Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
4. TCM Resident Doctor, Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
5. Internship, Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan

Academic Record:

1. Associate Editor, Session of Rheumatology, Frontiers in Medicine, Switzerland
2. Member of Adaptation Committee, Taiwan Herbal Pharmacopeia 4th Edition, Department of Chinese Medicine and Pharmacy, Ministry of Health and Welfare, Taipei, Taiwan

Association:

1. National Union of Chinese Medical Doctors’Association, R.O.C
2. Taipei Chinese Medical Association
3. Taiwain Clinical Chinese Medicine Association
4. Chinese Medical Association of Acupuncture
5. Taiwan Society of Chinese Medicine Otolaryngology
6. Taiwan Rheumatology Association
7. The Chinese Society of Immunology(CSI)
8. Taiwan Society for Integration of Chinese and Western Medicine

Awards:

1. "Best Teacher Award 2021", Taipei Veterans General Hospital, 2021
2. "Traditional Chinese Medicine excellent Academic Research Award": Chinese herbal medicine SS-1 inhibits T cell activation and ameliorates TH responses in Sjögren’s syndrome, Taipei Chinese Medical Association, Taipei, Taiwan, 2021
3. "Traditional Chinese Medicine excellent Academic Research Award": Stability of a Lupus Nephritis Case after One Year of Integrated Therapy, Taipei Chinese Medical Association, Taipei, Taiwan, 2021
4. "Traditional Chinese Medicine excellent Academic Research Award": TCM Insomnia OSCE Video education, Taipei, Taiwan, 2021
5. "Distinguished Clinical Teaching Physician Award", Taipei Veterans General Hospital", Veterans Affairs Council (VAC), R.O.C, 2020
6. "Traditional Chinese Medicine excellent Academic Research Award", National Union of Chinese Medical Doctors’Association, R.O.C, 2020
7. "Traditional Chinese Medicine excellent Academic Research Award": Integrated therapy decreases the mortality of patients with polymyositis and dermatomyositis: A Taiwan-wide population-based retrospective study , Taipei Chinese Medical Association, Taipei, Taiwan, 2020
8. "Traditional Chinese Medicine excellent Academic Research Award": Laser Acupuncture for Carpal Tunnel Syndrome: A Single-Blinded Controlled Study, Taipei Chinese Medical Association, Taipei, Taiwan, 2020
9. "Excellent Teacher Award", 108-2 , PBL, Faculty of Medicine, National Yang-Ming University, 2020
10. "Excellent Teacher Award", 108-1 , PBL, Faculty of Medicine, National Yang-Ming University, 2020
11. "Traditional Chinese Medicine excellent Academic Research Award", National Union of Chinese Medical Doctors’Association, R.O.C, 2019
12. "Traditional Chinese Medicine excellent Academic Research Award": Integrated Therapy Improve Urinary Total Protein in Patients with Lupus Nephritis: A Case Report , Taipei Chinese Medical Association, Taipei, Taiwan, 2019
13. "Best Teacher Award 2020", Taipei Veterans General Hospital, 2020
14. "Excellent Teacher Award", 107-2 , PBL, Faculty of Medicine, National Yang-Ming University, 2019
15. "Excellent Teacher Award", 107-2 , PBL, Faculty of Medicine, National Yang-Ming University, 2019
16. "Best Physician Award", Taipei Veterans General Hospital", Veterans Affairs Council (VAC), R.O.C, 2018
17. "Traditional Chinese Medicine excellent Academic Research Award", National Union of Chinese Medical Doctors’Association, R.O.C, 2018
18. "Excellent Teacher Award", 106-2 , PBL, Faculty of Medicine, National Yang-Ming University, 2018
19. "Best Teacher Award 2018", Taipei Veterans General Hospital, 2018
20. "Traditional Chinese Medicine excellent Academic Research Award", National Union of Chinese Medical Doctors’Association, R.O.C, 2017
21. "Best Teacher Award 2017", Taipei Veterans General Hospital", 2017
22. "Traditional Chinese Medicine excellent Academic Research Award": Integrative Therapy Decreases the Risk of Lupus Nephritis in Patients with Systemic Lupus Erythematosus: A Population-Based Retrospective Cohort Study , Taipei Chinese Medical Association, Taipei, Taiwan, 2017
23. "Traditional Chinese Medicine excellent Academic Research Award": The Core Pattern Analysis on Chinese Herbal Medicine for Sjögren's syndrome: A Nationwide Population-Based Study , Taipei Chinese Medical Association, Taipei, Taiwan, 2016
24. "Traditional Chinese Medicine excellent Academic Research Award": How to understand the TCM Zheng, Taipei Chinese Medical Association, Taipei, Taiwan, 2016
25. "Distinguished Clinical Teaching Physician Award", Taipei Veterans General Hospital", Veterans Affairs Council (VAC), R.O.C, 2015
26. "Best Intern Award", China Medical University Hospital, Taichung, Taiwan, 2010
27. "Oral Presentation Excellence Award" in Research Conference, China Medical University, Taichung, Taiwan, 2010

Research  Interest:

1. Traditional Chinese Medicine in Allergy, Immunology, Rheumatology：中醫過敏風濕免疫學 
2. TCM Clinical trial：中醫藥臨床試驗 
3. Sjögren syndrome：修格蘭氏症、乾燥症
4. Systemic Lupus Erythematosus：紅斑性狼瘡 
5. Systemic Sclerosis：硬皮症
6. Bioinformatics：生物資訊

Clinical expertise:

1. Sjögren syndrome/Sicca Syndrome (Dry Eye, Dry month)：修格蘭氏症 /乾燥症 (口乾、眼乾)
2. Systemic Lupus Erythematosus：紅斑性狼瘡 
3. Systemic Sclerosis：硬皮症
4. Rheumatoid arthritis：類風濕性關節炎
5. Ankylosing spondylitis：僵直性脊椎炎
6. Autoimmune Rheumatic Diseases：自體免疫風濕疾病
7. Dry Eye Syndrome/Keratoconjunctivitis：乾眼症
8. Allergic Rhinitis： 過敏性鼻炎 
9. Insomnia/ Sleep disorder：失眠/睡眠障礙 
10. Anxiety/Depressive disorder：焦慮、憂鬱症 
11. Chronic Fatigue Syndrome： 慢性疲勞症候群 
12. Sleep Obstructive Disease/Obstructive Sleep Apnea (OSA)： 睡眠呼吸中止症 
13. Gastrointestinal disorder：腸胃道疾病 
14. Gastroesophageal reflux disease (GERD)：胃食道逆流
15. Migraine：偏頭痛
16. Irritable Bowel Syndrome：大腸激躁症 
17. Dizziness/Vertigo Disorder： 頭昏/眩暈 
18. Hepatitis B/C： B/C型肝炎 
19. Myofascial pain syndrome：筋肌膜炎症候群 
20. Osteoarthritis：退化性關節炎 
21. Acupuncture & Moxibustion： 針灸

Ph.D. Thesis:

 (2012-2017, Ph.D. Candidate since 2014/06/13, Ph.D. since 2017/07)

<中藥臨床試驗暨轉譯醫學研究>

• 中文：中藥複方治療修格蘭氏症之療效評估及其抗氧化與免疫調控機轉之研究
• 英文：The Efficacy of Chinese Herbal Formula on Sjögren's syndrome and its Mechanism of Anti-oxidative and Immune Modulatory Effects

Contact Information:

• Ching-Mao Chang, M.D., Ph.D. Candidate (張清貿, C.M. Chang)
• Center for Traditional Medicine, Taipei Veterans General Hospital
• No.201, Sec. 2, Shipai Rd., Beitou District, Taipei City, Taiwan 11217, R.O.C
• TEL: +886-2-28757453 #304
• E-Mail: tcmcmc@gmail.com
• Blog: http://tcmcmc.blogspot.tw/

[文字雲] tcmcmc blogger 文字雲 20140629：頭痛

沒想到這一段時間是以「頭痛」為主

[研究] 中醫SCI國際期刊審稿

最近被某中醫前50％的SCI國際期刊邀請審稿，連續審稿兩篇PAPER，

其中一篇就只是說：

有一個OO病，我用中藥把病治好了，然後沒有告訴我用什麼藥

哎呀..............

我隨便花30分鐘去投研討會的POSTER都沒這麼簡略！！

[採訪錄音+演講照片] 2014/06/10 17:00 ~ 18:00 漢聲廣播電台 - 長青樹採訪：中醫是怎麼看病-談乾燥症(修格蘭氏症候群 Sjögren's syndrome)之中醫治療，受訪者：台北榮民總醫院傳統醫學部張清貿醫師

漢聲廣播電台 - 長青樹

電台頻率：FM106.5~AM1116~AM684

時間：2014/06/10 17:00 ~ 18:00

主題：中醫是怎麼看病-談乾燥症(修格蘭氏症候群 Sjögren's syndrome)之中醫治療

受訪者：張清貿醫師
             台北榮民總醫院傳統醫學部
             長庚大學臨床醫學研究所博士班

Youtube 48分鐘完整版廣播錄音

[論文發表] 該如何理解「證」？中醫證型現代研究的定性與定量

＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝＝

http://homepage.vghtpe.gov.tw/~clinmed/abst103/abst10303p189.htm

全文下載

:::

該如何理解「證」？-中醫證型現代研究的定性與定量

張清貿　施柏瑄　朱學亭　陳方佩

中醫常常強調「辨證論治」，「辨證」是「通過四診八綱、臟腑、病因、病機等中醫基礎理論，對病人表現的症狀、體徵進行綜合分析，辨別為何種證候」，而「論治」是「在辨證的基礎上，訂出治療措施」。因此需要有精確的辨證，才可以對應到適當的治則治法，再精準得出方藥來予以治療。不同中醫師辨證診斷的差異，往往只是由不同的視角看同一個證型。事實上「證」就是一種分類，辨證就是一種分類的方法，但目前對證的定性與定量始終沒有標準答案，可歸咎於兩個面向：1.中醫的證本身的基本定義不清楚（定性）。2.證型的量化程度不清楚（定量）。因此，近年來許多學者利用當時最先進的技術，莫不是要將證定義清楚並可被度量，使中醫複雜的證型可以透過簡單的幾個指標及測量值就可定義清楚與量化。因此知名替代與補充醫學領域的期刊Evidence-Based Complementary and Alternative Medicine (eCAM)，也在2012年針對「證」來提出探討，本文簡單論述中醫證型的相關現代研究，從生物資料學（bioinformatics）、基因體學（genomics）、代謝學（metabolomics）到實證醫學文獻回顧，疾病從糖尿病、失眠、肝癌到冠心病，在研究方法及疾病選擇上非常廣泛，雖然在現今講求臨床實證的條件下，中醫所做的努力仍不足，但也漸漸的、緩慢的往實　證療法邁進，不再只是停留在專書與老中醫之專家意見，相當值得鼓勵與學習。（臨床醫學 2014; 73: 189-95）

關鍵詞：		中醫藥（Chinese Medicine）、證（Zheng）、生物資訊學（Bioinformatics）、實證醫 學（Evidence-Based Medicine）

病態的社會

這是一個病態的社會，台灣現在的作法 (先聲明，我不是公務人員)：

公務員過很爽，民間過不爽，所以要把公務員拉下來，大家一起不爽

但是正面的作法應該是：

要跟公務員看齊，把大家薪水拉高，甚至要超過公務員

但是我沒看到老闆或是企業家有這樣的社會責任！

有得話就站出來呼籲吧！

重點不是作多久，是老闆要把員工一個人當兩個用，

事情當然做不完，老闆跟員工才會覺得做不完就加班。

但問題是，員工做不完就請兩個，

兩個人在五點下班，就可以去進修、購物、照顧小孩，

這不是最基本的嗎？所以是員工的問題嗎？

只要有牽涉到人的利益，就不是單純的統計問題

只要有牽涉到人的利益，就不是單純的統計問題，

所以就有了生物統計..........

[教育訓練］ 台北榮總總醫師訓練營

[臨床病例報告] 6個月後追蹤：15歲女性患者，異位性皮膚炎多年，服用中藥治療約6個月後之手部照片

異位性皮膚炎女性患者，服用中藥治療6個月後手部照片

張清貿醫師臨床註記：與6個月前初診時手部皮膚相比，病灶變小，粗糙程度改善明顯，紅斑紅疹幾乎快看不見，但患者自述偶而會癢，抓完破皮後會變嚴重，如果能克制不去抓，會改善更明顯

全程病情可參考：

[臨床病例報告] 15歲女性患者，異位性皮膚炎多年，服用中藥治療前後之手部照片 - 張清貿醫師 (2014/06/12更新)

國際期刊邀請當Reviewer

這幾個月開始被國際期刊邀請當Reviewer，
有的有SCI，有的沒SCI，有的中文，有的英文，

但是剛剛收到一篇最奇怪，
是在探討某城市保險套在潮濕天熱的天氣下保存品質，
題目很怪，寫得很怪，本來想直接退，甚至回信說不想審，

結果突然看到是「某非洲小國」的研究，
我突然想到李教授曾經說過的一個故事，
強的國家做頂尖研究是最基本的事，因為有很多資源，教育環境也很好，
李教授曾經審到一個小國家的PAPER，
基於鼓勵性質，就盡量通過，
因為小國家連生存都有問題，怎麼談得到教育，更何況是研究，就算駔研究能跟先進國家比嗎？

所以我決定效法李教授，
再怎麼樣我都要Major revised，
雖然這篇沒SCI，
但我一定要鼓勵他們，

如果沒SCI都被退稿，那以後他們還會想做研究嗎？

看完PAPER我覺得很生氣，
他們已經無法控制生育力了，為什麼連保險套品質都很差！！

[看診趣事] 失智症阿杯與患者的對話

今日門診有一個60幾歲的婆婆，當看護照顧一個80多歲的A阿杯，
婆婆每次來門診針灸，都會帶A阿杯來，
但是A阿杯有失智症，所以會到處亂跑，
婆婆每次都要我們幫忙看住A阿杯，
後來我想到一招，A阿杯來的時候我也送他針灸，幫他醒腦開竅，
這樣A阿杯就跑不了。

今天婆婆跟A阿杯又來了，
我依慣例幫A阿杯扎針，然後再幫隔壁B阿杯扎診，
這時候A阿杯就問B阿杯：「年輕人你幾歲啦。」
B阿杯：「我82。」
A阿杯：「你比我小4歲，我86。」
B阿杯：「我看不出來，你保養的真好。」
A阿杯：「我不要再多說了，不能再說廢話了。」

這時候我就跟B阿杯說：「A阿杯有失智症，我怕他亂跑，我都會幫他扎針定住，不然他每次都看他的看護在針灸，就開始想到處啪啪造。」

B阿杯：「不會阿，我看他思路清晰，對答如流。」
我：「歐，好，科科。」

過一下子.........大約1分鐘
A阿杯就再問B阿杯：「年輕人你幾歲啦。」
B阿杯：「我82。」
A阿杯：「你比我小4歲，我86。」
B阿杯：「真的阿。」
A阿杯：「我不要再多說了，不能再說廢話了。」

然後又過了1分鐘............
A阿杯又再問B阿杯：「年輕人你幾歲啦。」
B阿杯：「我82。」
A阿杯：「你比我小4歲，我86。」
B阿杯：「.............」
A阿杯：「我不要再多說了，不能再說廢話了。」

這時我對B阿杯說：「我沒騙你吧！！」

以上流程大概從B阿杯扎針到拔針，大概重複了5次，

2014/06/10 17:00 ~ 18:00 漢聲廣播電台 - 長青樹採訪：中醫是怎麼看病-談乾燥症(修格蘭氏症候群 Sjögren's syndrome)之中醫治療，受訪者：台北榮民總醫院傳統醫學部張清貿醫師

漢聲廣播電台 - 長青樹

電台頻率：FM106.5~AM1116~AM684

時間：2014/06/10 17:00 ~ 18:00

主題：中醫是怎麼看病-談乾燥症(修格蘭氏症候群 Sjögren's syndrome)之中醫治療

受訪者：張清貿醫師
               台北榮民總醫院傳統醫學部
               長庚大學臨床醫學研究所博士班

Sjögren's syndrome乾燥症中醫藥臨床試驗收案

每個禮拜三早上的Sjögren's syndrome乾燥症中醫藥臨床試驗收案，

我一早在半路早餐車都會買一杯大杯熱紅茶+兩顆飯糰，

學校老闆問我：「這是什麼？」

我說：「我每個禮拜收案都買兩顆飯糰，

一顆早餐吃，一顆午餐吃，

我預計吃200顆就可以畢業了，

所以我現在開始每個禮拜收案就給他吃三顆，

看可不可以提早畢業！！」

然後我就被學校老闆打.............

[演講照片] 20140525 林口長庚醫院台灣頭痛學會頭痛衛教種子教師培訓營 演講 - 頭痛中醫針灸及非藥物治療